Aging, Oxidative Stress and Antioxidants

Oxidative Stress and Human Disease: a Review

Background: The human body needs both types of oxidants (free radicals) and antioxidants for normal metabolism, signal transduction mechanism, and the order of cellular activity. Free radicals can be either harmful or helpful to the body, in fact, they play a dual role as both toxic and beneficial compounds. The human body has the natural antioxidant defense mechanism to counteract the free rad...

Age related changes in indices of bone metabolism and oxidative stress in Postmenopausal women in Southern Nigeria

Background and Objectives: Oxidative stress (OS) associated with estrogen deficiency in menopause has been implicated in various complications of menopause. Some indices of OS, bone metabolism, and uric acid (UA) in postmenopausal women were assessed as possible predictors of gouty osteoarthritis. Materials and Methods: This case-control study enrolled 40 postmenopausal women and 60 premenopau...

Molecular mechanisms of oxidative stress in aging: free radicals, aging, antioxidants and disease

The Mediterranean Lifestyle as a Non-Pharmacological and Natural Antioxidant for Healthy Aging.

Oxidative stress has been suggested to affect age-associated physiological dysfunction. Therefore, it is speculated that antioxidant supplements could have a potential role in preventing age-related diseases and death. Among different dietary habits, the highly antioxidant Mediterranean dietary pattern, which includes high vegetable and fruit intake, consumption of legumes, cereals, and fish, l...

Achieving the Balance between ROS and Antioxidants: When to Use the Synthetic Antioxidants

Free radical damage is linked to formation of many degenerative diseases, including cancer, cardiovascular disease, cataracts, and aging. Excessive reactive oxygen species (ROS) formation can induce oxidative stress, leading to cell damage that can culminate in cell death. Therefore, cells have antioxidant networks to scavenge excessively produced ROS. The balance between the production and sca...

A review on nutrition and skin aging

Background: Skin reflects the general health status and is not an exception in the process of aging. Intervention studies indicate that it is possible to delay skin aging and improve skin conditions through diet-based anti-aging strategies. The purpose of the current work was to review recent existing literature regarding the role of nutrition, for and against skin aging processes.Method: This ...